Let's be practical. The cost of an arrow is much more expensive than a SCUD or an Shahab missile. And we can assume Iran is piling up missiles: We know that, that is the Hezbollah/Hamas strategy. So if Irak had 1000 skud we can expect Iran having much more Shahab.
The obvious strategy for Iran would be to flood Israel Military defense before sending a nuclear/chemical missiles. With 200 arrows missiles, Israel is no match. The best strategy would be for the Arrow to be able to detect nuclear missile (through radiation emotion) first. Israel would have no choice but sacrificing their own population to ensure the availability of the arrow missile. CONCLUSION : Israel cannot minimize heavy casualties only if Iran nuclear capability is destroyed.